Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.67 |
| ▸ | CPA3 | P15088 | 1/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436394 | 0.90 | LDHA (0.76) | LDHAPPARGKMT2A | |
| SCHEMBL12494157 | 0.86 | LDHA (0.71) | LDHACPA3PPARGKMT2A | |
| SCHEMBL12493566 | 0.86 | LDHA (0.71) | LDHACPA3PPARGKMT2A | |
| SCHEMBL4453569 | 0.85 | PPARG (0.72) | LDHAPPARGKMT2A | |
| SCHEMBL12191490 | 0.85 | PPARG (0.72) | LDHAPPARGKMT2A | |
| SCHEMBL6177184 | 0.85 | CYP1A2 (0.69) | LDHACPA3FOLH1PPARGKMT2A | |
| SCHEMBL11270370 | 0.84 | LDHA (0.54) | LDHAACEPPARG | |
| SCHEMBL6178867 | 0.83 | LDHA (0.67) | LDHACPA3FOLH1PPARGKMT2A | |
| SCHEMBL21194011 | 0.83 | LDHA (0.67) | LDHAPPARGKMT2A | |
| SCHEMBL31344391 | 0.83 | LDHA (0.67) | LDHAPPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285858-A | ANTIHEMOPHILIC FACTOR; HEMOSTATIC AGENTS; ANTICOAGULANTS AND COAGULANTS | MT. SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF N.Y. (US) | 1981-08-25 | — | — | US | disclosed |
| EP-0029659-A2 | Vasopressin analogs, processes for their production and a method of treating mammals | Cort, Joseph H. (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4210636-A | Antisecretory polypeptides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
| US-4180500-A | Polypeptides related to somatostatin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-12-25 | — | — | US | disclosed |