Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381717 | 0.86 | IDO1 (0.55) | IDO1TAAR1L3MBTL1MAPTKDM4E | |
| SCHEMBL29650488 | 0.86 | IDO1 (0.55) | IDO1TAAR1L3MBTL1MAPTKDM4E | |
| SCHEMBL380362 | 0.82 | IDO1 (0.56) | LTA4HSLC6A4IDO1TAAR1MAPT | |
| SCHEMBL6476003 | 0.80 | IDO1 (0.54) | LTA4HSLC6A4IDO1TAAR1MAPT | |
| SCHEMBL7282070 | 0.79 | LTA4H (0.62) | ABCB1LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5689697 | 0.75 | IDO1 (0.48) | IDO1TAAR1LMNATSHRCHRM2 | |
| SCHEMBL18725306 | 0.75 | ABCB1 (0.48) | ABCB1LTA4HSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9879256 | 0.74 | IDO1 (0.52) | LTA4HSLC6A4IDO1TAAR1MAPT | |
| SCHEMBL7710320 | 0.74 | IDO1 (0.47) | IDO1TAAR1L3MBTL1MAPTLMNA | |
| SCHEMBL11461076 | 0.74 | IDO1 (0.47) | IDO1TAAR1L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292437-A | USING A PALLADIUM-ORTHO-SUBSTITUTED TRIARYL PHOSPHINE COMPLEX AS CATALYST FOR THE CARBONYLATION OF PROPYLENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-29 | — | — | US | disclosed |