Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359078 | 0.86 | SMN1; SMN2 (0.37) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL11360819 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL11373381 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL27618647 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL11364194 | 0.79 | NPC1 (0.38) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL1714565 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL14367311 | 0.78 | NPC1 (0.41) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL11376448 | 0.78 | SMN1; SMN2 (0.32) | SMN1; SMN2NPC1RAB9ALMNAMAOB | |
| SCHEMBL11359074 | 0.74 | ADAMTS4 (0.36) | SMN1; SMN2NPC1RAB9AMAOBMAPT | |
| SCHEMBL11360815 | 0.74 | NPC1 (0.34) | SMN1; SMN2NPC1RAB9ALMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247548-A | 7α-Methoxycephalosporin derivatives and their pharmaceutical compositions having antibacterial activity | SANKYO COMPANY LIMITED (JP) | 1981-01-27 | — | — | US | disclosed |