SCHEMBL11359201

SCHEMBL11359201

CC(CCc1ccccc1)NCC(=O)c1ccc(O)c(C(N)=O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 7/20 0.67
ADRA1D P25100 4/20 0.65
ADRA1A P35348 4/20 0.65
ADRA1B P35368 4/20 0.65
ADRB1 P08588 4/20 0.65
HPGD P15428 3/20 0.65
ADRB2 P07550 3/20 0.65
ALDH1A1 P00352 3/20 0.65
CYP2D6 P10635 2/20 0.65
ADRA2A P08913 2/20 0.65
KDM4E B2RXH2 2/20 0.65
LMNA P02545 2/20 0.65
HSD17B10 Q99714 2/20 0.65
HTR1A P08908 1/20 0.65
SLC6A2 P23975 1/20 0.65
SLC6A4 P31645 1/20 0.65
OPRM1 P35372 1/20 0.65
DRD3 P35462 1/20 0.65
HTR2B P41595 1/20 0.65
SLC6A3 Q01959 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11351806 1.00 DPP4 (0.67) DPP4ADRA1DADRA1AADRA1BADRB1
Hydrochloric Acid SCHEMBL29394332 0.99 DPP4 (0.66) DPP4ADRA1DADRA1AADRA1BADRB1
SCHEMBL4983444 0.87 DPP4 (0.64) DPP4ADRA1DADRA1AADRA1BADRB1
Hydrochloric Acid SCHEMBL4987086 0.86 DPP4 (0.62) DPP4ADRA1DADRA1AADRA1BADRB1
SCHEMBL11884220 0.81 ADRB1 (0.67) DPP4ADRA1DADRA1AADRA1BADRB1
Hydrochloric Acid SCHEMBL6931345 0.81 DPP4 (0.57) DPP4ADRA1DADRA1AADRA1BADRB1
SCHEMBL11424471 0.80 DPP4 (0.61) DPP4ADRA1DADRA1AADRA1BADRB1
SCHEMBL10820346 0.80 ADRB1 (0.82) DPP4ADRA1DADRA1AADRA1BADRB1
SCHEMBL28670711 0.79 KDM4E (0.44) ADRA1DADRA1AADRA1BADRB1HPGD
Dilevalol SCHEMBL79468 0.79 ADRB1 (1.00) ADRA1DADRA1AADRA1BADRB1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017098520-A1 PROCESS FOR THE PREPARATION OF LABETALOL HYDROCHLORIDE prscDAVALURI RAMAMOHAN RAO (IN) 2017-06-15 WO claimed
EP-0009702-B1 A PHENYLALKYLAMINOETHYLSALICYLAMIDE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT SCHERING CORPORATION (US) 1981-11-04 EP claimed
CN-118575517-A Connection establishment method and device 北京小米移动软件有限公司 2024-08-30 CN disclosed
WO-2017098520-A1 PROCESS FOR THE PREPARATION OF LABETALOL HYDROCHLORIDE prscDAVALURI RAMAMOHAN RAO (IN) 2017-06-15 WO disclosed
WO-2017098520-A1 PROCESS FOR THE PREPARATION OF LABETALOL HYDROCHLORIDE prscDAVALURI RAMAMOHAN RAO (IN) 2017-06-15 WO disclosed
EP-0009702-B1 A PHENYLALKYLAMINOETHYLSALICYLAMIDE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT SCHERING CORPORATION (US) 1981-11-04 EP disclosed
EP-0009702-A1 A phenylalkylaminoethylsalicylamide, its preparation and pharmaceutical compositions containing it SCHERING CORPORATION (US) 1980-04-16 EP disclosed