Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 8/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900473 | 0.87 | PDE7A (0.62) | PDE7ANPC1RAB9AGSTP1GSTM2 | |
| SCHEMBL6191726 | 0.87 | PDE7A (0.62) | PDE7ANPC1RAB9AGSTP1GSTM2 | |
| SCHEMBL11330772 | 0.81 | ALDH1A1 (0.53) | PDE7ANPC1GSTP1GSTM2HSD17B10 | |
| SCHEMBL6811842 | 0.78 | PDE7A (0.51) | PDE7APDE4BPDE4DPDE7BHSD17B10 | |
| SCHEMBL6815838 | 0.77 | PDE7A (0.56) | PDE7ANPC1RAB9APDE4BPDE4D | |
| SCHEMBL8308859 | 0.76 | PDE7A (1.00) | PDE7APDE4BPDE4DPDE7BHSD17B10 | |
| SCHEMBL11707852 | 0.75 | ALDH1A1 (0.74) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8395124 | 0.75 | GSTP1 (0.50) | NPC1RAB9AGSTP1GSTM2HSD17B10 | |
| SCHEMBL8399947 | 0.75 | ALDH1A1 (0.43) | NPC1RAB9AGSTP1GSTM2ALDH1A1 | |
| SCHEMBL27581742 | 0.74 | PDE7A (0.75) | PDE7APDE4BPDE4DPDE7BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294986-A | Novel para-phenylalkoxy phenylurea and thiourea compounds and herbicidal use thereof | AMERICAN CYANAMID CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4289903-A | PREEMERGENCE AND POSTEMERGENCE | AMERICAN CYANAMID COMPANY (US) | 1981-09-15 | — | — | US | disclosed |