Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimetozine SCHEMBL114786 | 0.79 | MAPT (0.72) | MAPTPOLBKMT2ACYP1A2GAA | |
| SCHEMBL11353914 | 0.75 | SMN1; SMN2 (0.73) | MAPTPOLBKMT2ACYP1A2CYP2C9 | |
| Tritiozine SCHEMBL1170764 | 0.75 | MAPT (1.00) | MAPTPOLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL366113 | 0.73 | EPHX1 (0.49) | POLBTSHRKDM4EKMT2ACYP1A2 | |
| SCHEMBL24829823 | 0.72 | SMN1; SMN2 (0.60) | KMT2ASMN1; SMN2GAANPSR1TP53 | |
| SCHEMBL11371844 | 0.72 | MAPT (0.55) | MAPTPOLBTSHRKDM4EKMT2A | |
| SCHEMBL8247308 | 0.72 | CYP1A2 (1.00) | POLBTSHRKDM4ELMNAKMT2A | |
| SCHEMBL23962408 | 0.71 | TSHR (0.57) | POLBTSHRKDM4EKMT2ACYP1A2 | |
| SCHEMBL29596492 | 0.71 | MAPT (0.68) | MAPTPOLBKMT2AGAARAB9A | |
| SCHEMBL10022931 | 0.71 | RAB9A (0.64) | MAPTPOLBKMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252804-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | METABIO-JOULLIE (FR) | 1981-02-24 | — | — | US | claimed |
| US-4252804-A | TRANQUILIZERS, ANTICONVULSANTS, MUSCLE RELAXANTS | METABIO-JOULLIE (FR) | 1981-02-24 | — | — | US | disclosed |