Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1136296 | 1.00 | SMN1; SMN2 (0.35) | SMN1; SMN2KMT2ATDP1GSK3AGSK3B | |
| SCHEMBL14441020 | 0.86 | ALDH1A1 (0.36) | SMN1; SMN2KMT2ATDP1GSK3AGSK3B | |
| SCHEMBL9497808 | 0.82 | CYP4F2 (0.40) | KMT2ATDP1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL1136249 | 0.82 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL14441019 | 0.82 | CYP19A1 (0.36) | CYP19A1 | |
| SCHEMBL1136226 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2KMT2ATDP1GSK3AGSK3B | |
| SCHEMBL10745568 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2ATDP1GSK3AGSK3B | |
| SCHEMBL1135557 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2KMT2ATDP1GSK3AGSK3B | |
| SCHEMBL1136248 | 0.79 | CYP19A1 (0.40) | KMT2ACYP19A1GAAHPGD | |
| SCHEMBL13251702 | 0.74 | SLC18A3 (0.33) | SMN1; SMN2KMT2AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2218788-B1 | Process for the preparation of optically active cyclopentenones | WEI SHIH-YI (TW) | 2016-08-24 | — | — | EP | disclosed |
| US-8546114-B2 | Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom | CHIROGATE INTERNATIONAL INC. (TW) | 2013-10-01 | — | — | US | disclosed |
| US-8546114-B2 | Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom | CHIROGATE INTERNATIONAL INC. (TW) | 2013-10-01 | — | — | US | disclosed |
| US-8546114-B2 | Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom | CHIROGATE INTERNATIONAL INC. (TW) | 2013-10-01 | — | — | US | disclosed |
| EP-1811037-B1 | Optically active cyclopentenones for use in the peparation of prostaglandins | WEI SHIH-YI (TW) | 2011-02-23 | — | — | EP | disclosed |
| EP-2218788-A1 | Process for the preparation of optically active cyclopentenones | Chirogate International Inc. (TW) | 2010-08-18 | — | — | EP | disclosed |
| EP-1811037-A1 | Process for the preparation of optically active cyclopentenones | Chirogate International Inc. (TW) | 2007-07-25 | — | — | EP | disclosed |
| US-20070166809-A1 | Processes for the preparations of optically active cyclopentenones and cyclopentenones prepared therefrom | CHIROGATE INTERNATIONAL INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070166809-A1 | Processes for the preparations of optically active cyclopentenones and cyclopentenones prepared therefrom | CHIROGATE INTERNATIONAL INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070166809-A1 | Processes for the preparations of optically active cyclopentenones and cyclopentenones prepared therefrom | CHIROGATE INTERNATIONAL INC. | 2007-07-19 | — | — | US | disclosed |