SCHEMBL11363

SCHEMBL11363

Nc1ncnc2[nH]ncc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 2/20 1.00
RET P07949 1/20 1.00
PI4KA P42356 1/20 1.00
LRRK2 Q5S007 1/20 1.00
PI4K2B Q8TCG2 1/20 1.00
PI4K2A Q9BTU6 1/20 1.00
PI4KB Q9UBF8 1/20 1.00
PDPK1 O15530 1/20 0.57
CHEK1 O14757 1/20 0.55
AURKA O14965 1/20 0.55
MAPK1 P28482 2/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGDS O60760 1/20 0.49
MKNK1 Q9BUB5 3/20 0.46
CYP1A2 P05177 2/20 0.46
CCNT1 O60563 1/20 0.46
CCNA2 P20248 1/20 0.46
CDK2 P24941 1/20 0.46
CDK9 P50750 1/20 0.46
CCNA1 P78396 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351045 1.00 XDH (1.00) XDHRETPI4KALRRK2PI4K2B
Hydrochloric Acid SCHEMBL1741653 0.98 XDH (0.96) XDHRETPI4KALRRK2PI4K2B
Hydrochloric Acid SCHEMBL30403903 0.98 XDH (0.96) XDHRETPI4KALRRK2PI4K2B
Hydrochloric Acid SCHEMBL14742346 0.98 XDH (0.96) XDHRETPI4KALRRK2PI4K2B
Trifluoroacetic Acid SCHEMBL30405325 0.83 RET (0.69) XDHRETPI4KALRRK2PI4K2B
Trifluoroacetic Acid SCHEMBL30718192 0.83 RET (0.69) XDHRETPI4KALRRK2PI4K2B
Aminacrine SCHEMBL1342786 0.80 PI4KA (0.65) XDHRETPI4KALRRK2PI4K2B
SCHEMBL13257839 0.78 PI4KA (0.64) XDHRETPI4KALRRK2PI4K2B
SCHEMBL30767866 0.78 PI4KA (0.64) XDHRETPI4KALRRK2PI4K2B
SCHEMBL30767863 0.78 PI4KA (0.64) XDHRETPI4KALRRK2PI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2737 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637863-B2 Construction material DAKIP B.V. (NL) 2026-05-26 US claimed
EP-4531856-B1 BRUTON'S KINASE INHIBITORS FOR THE TREATMENT OF A SUDDEN ALLERGIC REACTION ALK ABELLO AS (DK) 2026-04-22 EP claimed
US-20250215007-A1 PREPARATION METHOD FOR HEAT-RESISTANT ENERGETIC MATERIAL PTO NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-07-03 US claimed
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-118930550-A Chlorogenic acid derivative and preparation method and application thereof 湖北徽博生物科技有限公司 2024-11-12 CN claimed
US-20240216377-A1 HETEROCYCLYLAMINES AS PI3K INHIBITORS INCYTE CORPORATION 2024-07-04 US claimed
CN-115572297-B Pyrazolopyrimidine-containing o-phenylenediamine derivative, and preparation method and application thereof 山东大学 2024-04-26 CN claimed
CN-117820320-A Preparation method of heat-resistant energetic material PTO 南京理工大学 2024-04-05 CN claimed
US-20230365570-A1 COMPOUNDS WITH GLUCOCORTICOID SPARING EFFECTS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-11-16 US claimed
EP-0231605-B1 RIBOFLAVIN PRODUCTION WITH YEAST ZeaGen, Inc. (US) 1993-04-07 EP claimed
EP-0288949-B1 PROCESS FOR THE PREPARATION OF TABULAR SILVER CHLORIDE EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-28 EP claimed
EP-0503700-A1 Method for the preparation of iodobromide emulsions containing monodisperse tabular grains AGFA-GEVAERT N.V. (BE) 1992-09-16 EP claimed
US-5035992-A Precipiating on cores E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-30 US claimed
EP-0430196-A1 Process for stabilization of high-chloride crystals with modified crystal habit using bromide shells E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-06-05 EP claimed
EP-0304908-B1 PROCESS FOR THE PREPARATION OF OCTAHEDRAL SILVER CHLORIDE-CONTAINING EMULSIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-20 EP claimed
US-4804621-A USING A GELATIN DISPERSION AND AN ORGANIC HETEROCYCLIC COMPOUND SUCH AS AN AMINO-AZA-PYRIMIDINE OR-S-TRIAZINE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-14 US claimed
US-4801523-A HETEROCYCLIC NITROGEN COMPOUND AS CRYSTAL MODIFIER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-01-31 US claimed
EP-0231605-A2 Riboflavin production with yeast ZeaGen, Inc. (US) 1987-08-12 EP claimed
US-4267324-A BY REACTION OF FORMAMIDINE AND 3-AMINO-4-CYANOPYRAZOLE POLAROID CORPORATION (US) 1981-05-12 US claimed