SCHEMBL11364152

SCHEMBL11364152

CC1CC(=O)NN=C1c1ccc2oc(O)nc2c1

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.59
PDE3B Q13370 1/20 0.55
PDE3A Q14432 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7331168 0.87 GPR119 (0.62) GPR119
SCHEMBL11360566 0.86 GPR119 (0.58) GPR119PDE3BPDE3A
SCHEMBL9687281 0.86 GPR119 (0.59) GPR119PDE3BPDE3A
SCHEMBL7297936 0.84 GPR119 (0.56) GPR119PDE3BPDE3A
SCHEMBL11358817 0.84 GPR119 (0.56) GPR119PDE3BPDE3A
SCHEMBL10519316 0.82 GPR119 (0.69) GPR119
SCHEMBL11095811 0.81 GPR119 (0.53) GPR119PDE3BPDE3A
SCHEMBL11097177 0.81 GPR119 (0.53) GPR119PDE3BPDE3A
SCHEMBL11359505 0.81 GPR119 (0.53) GPR119PDE3BPDE3A
SCHEMBL10522354 0.81 GPR119 (0.83) GPR119PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034743-A1 Benzoxazoles, their preparation and their use as medicines Dr. Karl Thomae GmbH (DE) 1981-09-02 EP disclosed