Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376091 | 0.93 | KDM4E (0.36) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL7903522 | 0.88 | KDM4E (0.39) | ALDH1A1KDM4ETDP1TP53CHRNA7 | |
| SCHEMBL23921031 | 0.80 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL15579128 | 0.80 | ALDH1A1 (0.33) | ALDH1A1KDM4ETDP1CHRNA7 | |
| SCHEMBL23920920 | 0.75 | MEN1 (0.35) | ALDH1A1MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL13632435 | 0.74 | HRH3 (0.35) | ALDH1A1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL4395137 | 0.74 | KDM4E (0.35) | ALDH1A1MEN1KMT2AKDM4ECHRNA7 | |
| SCHEMBL10109539 | 0.74 | MEN1 (0.49) | ALDH1A1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL11570613 | 0.74 | — | — | |
| SCHEMBL8215870 | 0.74 | HRH3 (0.41) | ALDH1A1MEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264753-A | USING AN ORGANO LITHIUM AND DIHETEROCYCLIC BRIDGED AMINE AS CATALYST SYSTEM | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4247418-A | ORGANO-LITHIUM COMPOUND WITH A BICYCLIC AMINE | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-01-27 | — | — | US | disclosed |