SCHEMBL11364941

SCHEMBL11364941

O=C(O)CC=CC(O)CO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
CYP2D6 P10635 1/20 0.50
ALOX15 P16050 1/20 0.50
AKR1B1 P15121 1/20 0.40
HDAC2 Q92769 1/20 0.39
OR51E2 Q9H255 1/20 0.35
PAM P19021 1/20 0.34
TET2 Q6N021 3/20 0.31
KDM4A O75164 2/20 0.31
KDM4C Q9H3R0 2/20 0.31
KDM2A Q9Y2K7 2/20 0.31
TET3 O43151 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
MEN1 O00255 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11111135 0.94 ALDH1A1 (0.44) ALDH1A1CYP2D6ALOX15AKR1B1HDAC2
SCHEMBL4434336 0.79 ALDH1A1 (0.48) ALDH1A1CYP2D6ALOX15HDAC2PAM
SCHEMBL28856409 0.77
SCHEMBL27849820 0.76 CYP2D6 (0.44) ALDH1A1CYP2D6ALOX15HDAC2PAM
SCHEMBL8733627 0.73
SCHEMBL8733629 0.73
SCHEMBL28725974 0.71 PPARG (0.56)
SCHEMBL15013806 0.71
SCHEMBL15013805 0.71
SCHEMBL23927632 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0012367-B1 METHOD FOR THE PREPARATION OF VINYLGLYCOL ESTERS BASF Aktiengesellschaft (DE) 1981-11-11 EP disclosed
EP-0012367-A1 Method for the preparation of vinylglycol esters BASF Aktiengesellschaft (DE) 1980-06-25 EP disclosed