Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 10/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11369280 | 0.99 | CYP2J2 (0.71) | CYP2J2CYP3A4CYP2C9CYP2B6MEN1 | |
| SCHEMBL11379129 | 0.94 | CYP2J2 (0.63) | CYP2J2CYP3A4MEN1NPC1CACNA1F | |
| SCHEMBL11377421 | 0.92 | CYP2J2 (0.64) | CYP2J2CYP3A4CYP2C9CYP2B6LMNA | |
| SCHEMBL11372307 | 0.91 | CYP2J2 (0.63) | CYP2J2CYP3A4CYP2C9CYP2B6LMNA | |
| SCHEMBL11376047 | 0.87 | CYP2J2 (0.58) | CYP2J2CYP3A4CYP2C9CYP2B6LMNA | |
| SCHEMBL11371018 | 0.85 | CYP2J2 (0.55) | CYP2J2CYP3A4CYP2C9CYP2B6MEN1 | |
| SCHEMBL11826925 | 0.84 | CYP2J2 (1.00) | CYP2J2CYP3A4CYP2C9CYP2B6NPC1 | |
| Terfenadone SCHEMBL11364486 | 0.84 | CYP2J2 (1.00) | CYP2J2CYP3A4CYP2C9CYP2B6NPC1 | |
| Hydrochloric Acid SCHEMBL11830971 | 0.83 | CYP2J2 (0.94) | CYP2J2CYP3A4CYP2C9CYP2B6 | |
| Terfenadone SCHEMBL11801242 | 0.83 | CYP2J2 (0.98) | CYP2J2CYP3A4CYP2C9CYP2B6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | claimed |
| US-4285957-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4254129-A | ANTIALLERGENS, BRONCHODILATORS, ANTIHISTAMINES; 4-DIPHENYLMETHYL PIPERIDINO-ALKANOLS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |