Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 12/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11371018 | 0.94 | CYP2J2 (0.55) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL11364979 | 0.91 | CYP2J2 (0.73) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| Hydrochloric Acid SCHEMBL11369280 | 0.90 | CYP2J2 (0.71) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL11377421 | 0.90 | CYP2J2 (0.64) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL3737586 | 0.85 | CYP2J2 (0.82) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL11379129 | 0.85 | CYP2J2 (0.63) | CYP2J2CYP3A4KCNH2LMNAHRH1 | |
| SCHEMBL11376047 | 0.85 | CYP2J2 (0.58) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL11393150 | 0.82 | CYP2J2 (0.68) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 | |
| SCHEMBL11379114 | 0.80 | OPRD1 (0.47) | CYP2J2KCNH2LMNAHRH1DRD3 | |
| SCHEMBL11826925 | 0.78 | CYP2J2 (1.00) | CYP2J2CYP3A4CYP2C9CYP2B6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4285958-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
| US-4254130-A | ANTIALLERGENS | RICHARDSON-MERRELL INC. (US) | 1981-03-03 | — | — | US | disclosed |