Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11361211 | 1.00 | HCAR2 (0.52) | HCAR2KEAP1NFE2L2CA12AKR1B10 | |
| SCHEMBL7598652 | 0.87 | — | — | |
| SCHEMBL7598644 | 0.87 | — | — | |
| SCHEMBL5826328 | 0.81 | — | — | |
| SCHEMBL2936276 | 0.79 | — | — | |
| SCHEMBL177747 | 0.77 | HCAR2 (0.80) | HCAR2KEAP1NFE2L2CA12AKR1B10 | |
| SCHEMBL178194 | 0.77 | HCAR2 (0.80) | HCAR2KEAP1NFE2L2CA12AKR1B10 | |
| SCHEMBL177748 | 0.77 | HCAR2 (0.80) | HCAR2KEAP1NFE2L2CA12AKR1B10 | |
| SCHEMBL38663531 | 0.74 | AKR1B10 (0.54) | HCAR2CA12AKR1B10CA1CA2 | |
| SCHEMBL2911353 | 0.74 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2CA12AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30810-E | HEAT STABILIZERS FOR POLYMERS | THIOKOL CORPORATION (US) | 1981-12-01 | — | — | US | disclosed |
| US-RE30032-E | POLYMER STABILIZERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1979-06-12 | — | — | US | disclosed |
| US-3979359-A | STABILIZERS FOR VINYL- AND VINYLIDENE HALIDE POLYMERS | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-09-07 | — | — | US | disclosed |