Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.48 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359372 | 0.90 | TBXA2R (0.53) | GAANPSR1TSHRALDH1A1TP53 | |
| SCHEMBL9129860 | 0.87 | TSHR (0.65) | HTTGAANPSR1TSHRALDH1A1 | |
| SCHEMBL10460676 | 0.86 | CYP4F2 (0.51) | HTTGAAALDH1A1TBXA2RTBXAS1 | |
| SCHEMBL11104229 | 0.86 | MAPT (0.54) | TSHRALDH1A1SMN1; SMN2POLBTBXA2R | |
| SCHEMBL11339358 | 0.85 | TBXA2R (0.60) | HTTALDH1A1SGMS1TBXA2RTBXAS1 | |
| SCHEMBL11364339 | 0.84 | PPARA (0.51) | HTTGAANPSR1TSHRALDH1A1 | |
| SCHEMBL11366850 | 0.84 | PPARA (0.51) | HTTGAANPSR1TSHRALDH1A1 | |
| SCHEMBL11361292 | 0.83 | PTGS2 (0.53) | HTTGAANPSR1TSHRALDH1A1 | |
| SCHEMBL11362199 | 0.82 | GAA (0.58) | HTTGAANPSR1TSHRALDH1A1 | |
| SCHEMBL10463756 | 0.81 | KMT2A (0.52) | HTTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258058-A | Phenoxyalkylcarboxylic acid compounds and thrombocyte-aggregation inhibition | BOEHRINGER MANNHEIM GMBH (DE) | 1981-03-24 | — | — | US | disclosed |