Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687656 | 0.72 | KMT2A (0.50) | MAPK1POLBADRA2CELANESMN1; SMN2 | |
| SCHEMBL11370555 | 0.72 | MAPK1 (0.50) | MAPK1POLBADRA2CELANESMN1; SMN2 | |
| SCHEMBL11369126 | 0.72 | MAPK1 (0.50) | MAPK1POLBADRA2CELANESMN1; SMN2 | |
| SCHEMBL11365894 | 0.70 | POLB (0.48) | MAPK1POLBADRA2CELANESMN1; SMN2 | |
| SCHEMBL11691862 | 0.70 | POLB (0.48) | MAPK1POLBADRA2CELANESMN1; SMN2 | |
| SCHEMBL11437107 | 0.70 | MAPK1 (0.91) | MAPK1POLBADRA2CELANESMN1; SMN2 | |
| SCHEMBL11364967 | 0.69 | MAPK1 (0.42) | MAPK1POLBELANENOTUM | |
| SCHEMBL11363331 | 0.69 | POLB (1.00) | MAPK1POLBADRA2CELANEMEN1 | |
| SCHEMBL10381935 | 0.67 | POLB (0.45) | MAPK1POLBADRA2CELANE | |
| SCHEMBL4132942 | 0.65 | MAPK1 (0.48) | MAPK1POLBELANESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294973-A | Process for the preparation of diacylated 4-imidazolin-2-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4238618-A | Process for the preparation of diacylated 4-imidazolin-2-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |