Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29050324 | 0.74 | ACE (0.42) | MAPK1POLBNOTUMELANE | |
| SCHEMBL11735474 | 0.73 | BRD4 (0.38) | MAPK1POLBBRD4NOTUM | |
| SCHEMBL11737994 | 0.69 | BRD4 (0.40) | MAPK1POLBBRD4NOTUMELANE | |
| SCHEMBL11367207 | 0.69 | MAPK1 (0.52) | MAPK1POLBNOTUMELANE | |
| SCHEMBL15745863 | 0.66 | MAPK1 (0.33) | MAPK1POLB | |
| SCHEMBL8518184 | 0.66 | ELANE (0.41) | MAPK1ELANE | |
| SCHEMBL11641868 | 0.64 | MAPK1 (0.33) | MAPK1BRD4NOTUM | |
| SCHEMBL8209496 | 0.64 | NOTUM (0.36) | MAPK1POLBBRD4NOTUM | |
| SCHEMBL8209691 | 0.64 | NOTUM (0.36) | MAPK1POLBBRD4NOTUM | |
| SCHEMBL4335919 | 0.63 | NOTUM (0.39) | MAPK1POLBBRD4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4294973-A | Process for the preparation of diacylated 4-imidazolin-2-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-13 | — | — | US | disclosed |
| US-4238618-A | Process for the preparation of diacylated 4-imidazolin-2-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |