Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.39 |
| ▸ | GHSR | Q92847 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369427 | 0.98 | NPC1 (0.40) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL11380886 | 0.89 | RPS6KA2 (0.44) | RAB9AMEN1KMT2AHPGDRPS6KA2 | |
| SCHEMBL11379160 | 0.88 | MAPT (0.44) | RAB9AMEN1KMT2AHPGDRPS6KA2 | |
| SCHEMBL11380866 | 0.88 | NOX1 (0.39) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL11441219 | 0.85 | RPS6KA2 (0.41) | RAB9AMEN1KMT2AHPGDRPS6KA2 | |
| SCHEMBL11364534 | 0.84 | MAPT (0.41) | RAB9AMEN1KMT2AHPGDRPS6KA2 | |
| SCHEMBL11364764 | 0.84 | NPSR1 (0.40) | MEN1KMT2AHPGDRPS6KA2MAPT | |
| SCHEMBL11379713 | 0.83 | ALDH1A1 (0.40) | RAB9AMEN1KMT2AHPGDRPS6KA2 | |
| SCHEMBL11369563 | 0.83 | MAPT (0.42) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL11377384 | 0.82 | CYP3A4 (0.47) | NPC1RAB9AMEN1KMT2ARPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4187223-A | 3-[4-(Disubstituted-amino)phenyl]-3-(diphenylamino)phthalides | STERLING DRUG INC. (US) | 1980-02-05 | — | — | US | disclosed |
| US-4168378-A | THERMOGRAPHY, LEUCO DYES | STERLING DRUG INC. (US) | 1979-09-18 | — | — | US | disclosed |