Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357351 | 0.82 | KMT2A (0.39) | KDM4EKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11038077 | 0.77 | NUDT1 (0.40) | HSP90AA1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL8874173 | 0.73 | KDM4E (0.37) | HSP90AA1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL21273912 | 0.72 | HSP90AA1 (0.50) | HSP90AA1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL10986250 | 0.72 | HSP90AA1 (0.41) | HSP90AA1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL653958 | 0.69 | MEN1 (0.44) | HSP90AA1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL9178364 | 0.64 | KDM4E (0.40) | KDM4EKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL12495474 | 0.64 | SMN1; SMN2 (0.46) | KDM4EKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL10916068 | 0.64 | HSP90AA1 (0.75) | HSP90AA1KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL5234964 | 0.64 | KMT2A (0.37) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000681-B1 | AMINO-2 (OR -4) ALKYLTHIO-5 PYRIMIDINES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND COMPOSITION CONTAINING THEM | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-08-26 | — | — | EP | disclosed |
| EP-0000681-A1 | Amino-2 (or -4) alkylthio-5 pyrimidines, processes for their preparation, their use as herbicides and composition containing them | P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1979-02-07 | — | — | EP | disclosed |