Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11359619 | 0.90 | ALDH1A1 (0.49) | ALDH1A1MAPTTSHRHPGDLMNA | |
| SCHEMBL11366859 | 0.90 | MAPT (0.44) | ALDH1A1MAPTTSHRHPGDLMNA | |
| SCHEMBL11361250 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MAPTTSHRHPGDLMNA | |
| SCHEMBL11363847 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL11361458 | 0.79 | POLB (0.40) | ALDH1A1MAPTTSHRHPGDSMN1; SMN2 | |
| SCHEMBL11366836 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTTSHRHPGDLMNA | |
| SCHEMBL11413626 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTTSHRHPGDLMNA | |
| SCHEMBL11369619 | 0.78 | POLB (0.42) | ALDH1A1HPGDSMN1; SMN2POLBL3MBTL1 | |
| SCHEMBL11361649 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTTSHRHPGDLMNA | |
| SCHEMBL11365649 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDLMNASMN1; SMN2ALKBH5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4249934-A | 1,2-Alkylene-4-substituted urazole herbicides | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |