Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367561 | 0.88 | TTR (0.52) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11860702 | 0.86 | KDM4E (0.61) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11374511 | 0.81 | TTR (0.58) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11865259 | 0.79 | TTR (0.61) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL10454201 | 0.79 | TTR (0.64) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11768484 | 0.78 | KDM4E (0.47) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL68189 | 0.78 | TTR (0.83) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11868878 | 0.77 | TTR (0.56) | TTRKDM4EMEN1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL11749391 | 0.77 | TTR (0.81) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11860157 | 0.77 | KDM4E (0.65) | TTRKDM4EMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250097-A | (7-METHYL(2-HYDROXYETHYL)AMINO)SULFONYLXANTHONE-2-CARBOXYLIC ACID; ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1981-02-10 | — | — | US | disclosed |
| US-4232040-A | XANTHONE CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |