SCHEMBL68189

SCHEMBL68189

O=C(O)c1ccc2oc3ccc(C(=O)O)cc3c(=O)c2c1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 11/20 0.83
AKR1B1 P15121 1/20 0.66
KDM4E B2RXH2 1/20 0.64
MEN1 O00255 1/20 0.64
ALDH1A1 P00352 1/20 0.64
TP53 P04637 1/20 0.64
CYP2C9 P11712 1/20 0.64
HPGD P15428 1/20 0.64
PTGER1 P34995 1/20 0.64
PTGER3 P43115 1/20 0.64
PTGER2 P43116 1/20 0.64
KMT2A Q03164 1/20 0.64
PTGDR Q13258 1/20 0.64
HSD17B10 Q99714 1/20 0.64
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
MAPT P10636 1/20 0.52
GFER P55789 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
LTB4R Q15722 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11749391 0.98 TTR (0.81) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL11322640 0.93 TTR (0.80) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL21313809 0.91 TTR (0.71) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL1787556 0.91 TTR (1.00) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL11883817 0.91 NPC1 (0.74) TTRAKR1B1KDM4EMEN1ALDH1A1
Hydrochloric Acid SCHEMBL11367851 0.90 TTR (0.97) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL11768650 0.90 TTR (0.69) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL11376347 0.90 TTR (0.69) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL71110 0.90 TTR (0.68) TTRAKR1B1KDM4EMEN1ALDH1A1
SCHEMBL8949782 0.87 TTR (0.70) TTRAKR1B1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269419-A Polyimide applicable to FOLED substrate and preparation method thereof 湖南工业大学 2020-06-12 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20110007243-A1 LIQUID CRYSTAL DISPLAY DEVICE IPS ALPHA SUPPORT CO., LTD. (JP) 2011-01-13 US disclosed
US-4250182-A Pharmaceutical composition containing acridone compounds and method of using same BURROUGHS WELLCOME CO. (US) 1981-02-10 US disclosed
US-4041165-A TREATING DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1977-08-09 US disclosed
US-3957986-A Antiviral compositions containing bis-basic esters and amides of xanthene and xanthone RICHARDSON-MERRELL INC. (US) 1976-05-18 US disclosed
US-3953602-A DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1976-04-27 US disclosed
US-3937833-A DELAYED HYPERSENSITIVITY RICHARDSON-MERRELL INC. (US) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TTR 3513/4885AKR1B1 1027/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.