SCHEMBL11367478

SCHEMBL11367478

CCOc1ccc2c(c1)C(=O)C(O)=C(O)C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.62
L3MBTL1 Q9Y468 2/20 0.62
KMT2A Q03164 3/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 1/20 0.54
GAA P10253 1/20 0.54
CSNK2A2 P19784 1/20 0.48
CSNK2B P67870 1/20 0.48
CSNK2A1 P68400 1/20 0.48
CSNK2A3 Q8NEV1 1/20 0.48
CHRNA7 P36544 1/20 0.47
KDM4E B2RXH2 1/20 0.46
NQO1 P15559 1/20 0.45
ESR2 Q92731 1/20 0.45
HSD17B10 Q99714 1/20 0.45
POLB P06746 1/20 0.43
DNMT1 P26358 1/20 0.43
RAD52 P43351 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10883121 0.89 MAPT (0.70) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL11358368 0.86 MAPT (0.72) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL9643489 0.84 MAPT (0.59) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL2268303 0.84 MAPT (0.64) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL11368173 0.82 MAPT (0.67) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL11371731 0.82 MAPT (0.67) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL10887519 0.82 MAPT (0.67) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL9429530 0.81 MAPT (0.60) MAPTL3MBTL1KMT2ANPC1RAB9A
SCHEMBL5810326 0.79 LCK (0.56) MAPTKMT2AMEN1ALDH1A1ESR2
SCHEMBL11374736 0.79 MAPT (0.58) MAPTL3MBTL1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4255405-A 2,3-DIESTERS SYNTEX (U.S.A.) INC. (US) 1981-03-10 US disclosed