SCHEMBL10883121

SCHEMBL10883121

CCOc1ccc2c(c1)C(=O)c1cc(OCC)ccc1C2=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.70
L3MBTL1 Q9Y468 2/20 0.70
KMT2A Q03164 3/20 0.57
CHRNA7 P36544 1/20 0.57
MEN1 O00255 1/20 0.56
NPC1 O15118 1/20 0.56
ALDH1A1 P00352 1/20 0.56
GAA P10253 1/20 0.56
RAB9A P51151 1/20 0.56
NQO1 P15559 1/20 0.52
POLB P06746 1/20 0.51
DNMT1 P26358 1/20 0.51
RAD52 P43351 1/20 0.51
ESR2 Q92731 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CSNK2A2 P19784 1/20 0.49
CSNK2B P67870 1/20 0.49
CSNK2A1 P68400 1/20 0.49
CSNK2A3 Q8NEV1 1/20 0.49
PTPRC P08575 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268303 0.94 MAPT (0.64) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL10887519 0.93 MAPT (0.67) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL9429530 0.91 MAPT (0.60) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL9643489 0.90 MAPT (0.59) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL11367478 0.89 MAPT (0.62) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL10446471 0.84 MAPT (0.54) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL9627608 0.83 CDC25A (0.56) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL10525629 0.83 MAPT (0.52) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL9627399 0.83 MAPT (0.52) MAPTL3MBTL1KMT2ACHRNA7MEN1
SCHEMBL10692866 0.82 MAPT (0.55) MAPTL3MBTL1KMT2ACHRNA7MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0005379-B2 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1986-06-04 EP disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed