Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | GLA | P06280 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | PLAU | P00749 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29625000 | 1.00 | SCNN1A (0.53) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL507599 | 0.90 | NPSR1 (0.54) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL29987712 | 0.90 | NPSR1 (0.54) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23900531 | 0.87 | NPSR1 (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11737098 | 0.85 | NPSR1 (0.45) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12108294 | 0.85 | NPSR1 (0.48) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28798755 | 0.85 | NPSR1 (0.48) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL21335829 | 0.84 | NPSR1 (0.44) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14721302 | 0.83 | NPSR1 (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30206157 | 0.83 | NPSR1 (0.47) | SCNN1AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112442201-A | Preparation method of polyimide optical reflecting film | 宁波东旭成新材料科技有限公司 | 2021-03-05 | — | — | CN | claimed |
| WO-2011156355-A1 | PRODUCTION METHOD OF PHENYL GUANIDINE SALTS AND THEIR INTERMEDIATES | KAINOS MEDICINE, INC. (KR) | 2011-12-15 | — | — | WO | claimed |
| US-20250304590-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | Enterprise Therapeutics Limited (GB) | 2025-10-02 | — | — | US | disclosed |
| US-12371436-B2 | Substituted benzodiazoliums as ENaC inhibitors | Enterprise Therapeutics Limited (GB) | 2025-07-29 | — | — | US | disclosed |
| US-11935803-B2 | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate for mounting semiconductor with resin composition layer and semiconductor device | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-03-19 | — | — | US | disclosed |
| US-20240067653-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | Enterprise Therapeutics Limited (GB) | 2024-02-29 | — | — | US | disclosed |
| US-11739094-B2 | Substituted benzodiazoliums as ENaC inhibitors | Enterprise Therapeutics Limited (GB) | 2023-08-29 | — | — | US | disclosed |
| WO-2023283639-A1 | EPITHELIAL SODIUM CHANNEL (ENAC) INHIBITOR CONJUGATES AND METHODS FOR USE THEREOF | LUNG THERAPEUTICS, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| US-20230002356-A1 | COMPOUNDS AND USES THEREOF | PANO THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | US | disclosed |
| CN-110214141-B | Benzodiazolium compounds as ENaC inhibitors | 企业治疗学有限公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| CN-88103114-A | Heterogeneous ring compound | — | 1988-12-28 | — | — | CN | disclosed |
| CN-88103112-A | AMIDES | — | 1988-12-28 | — | — | CN | disclosed |
| EP-0293171-A1 | Pyrazinamide derivatives | ICI AMERICAS INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| EP-0293170-A1 | Aminomethylphenolic pyrazines, their preparation and use | ICI AMERICAS INC. (US) | 1988-11-30 | — | — | EP | disclosed |
| EP-0086564-B1 | ALKANOLAMINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-21 | — | — | EP | disclosed |
| US-4550111-A | BETA-ADRENERGIC BLOCKING AGENTS; DIURETICS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-10-29 | — | — | US | disclosed |
| EP-0086564-A1 | Alkanolamine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-08-24 | — | — | EP | disclosed |
| US-4087526-A | NATRIURETICS, DIURETICS | MERCK & CO., INC. (US) | 1978-05-02 | — | — | US | disclosed |
| US-3948895-A | CURING AGENTS FOR EPOXY RESINS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11739094-B2 | Substituted benzodiazoliums as ENaC inhibitors | NHERF1, SCNN1B, SCNN1A | SCNN1A 3/4885ALDH1A1 1058/4885KDM4E 3321/4885 |
| US-12371436-B2 | Substituted benzodiazoliums as ENaC inhibitors | NHERF1, SCNN1B, SCNN1A | SCNN1A 3/4885ALDH1A1 1058/4885KDM4E 3321/4885 |
| US-20240067653-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | NHERF1, SCNN1B, SCNN1A | SCNN1A 3/4885ALDH1A1 1179/4885KDM4E 3772/4885 |
| US-20230002356-A1 | COMPOUNDS AND USES THEREOF | HIF1AN, HIF1A, EGLN2 | SCNN1A 3328/4885ALDH1A1 229/4885KDM4E 919/4885 |
| US-20250304590-A1 | BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS | NHERF1, SCNN1B, SCNN1A | SCNN1A 3/4885ALDH1A1 1179/4885KDM4E 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.