Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | ERN1 | O75460 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367648 | 1.00 | MAPT (0.59) | MAPTNPSR1ERN1MAOBALDH1A1 | |
| SCHEMBL10464713 | 0.84 | CA1 (0.43) | MAPTNPSR1ERN1ALDH1A1RAB9A | |
| SCHEMBL10464714 | 0.84 | CA1 (0.43) | MAPTNPSR1ERN1ALDH1A1RAB9A | |
| SCHEMBL8038703 | 0.83 | MAPT (0.71) | MAPTNPSR1ERN1MAOBALDH1A1 | |
| SCHEMBL7115702 | 0.82 | FBP1 (0.42) | MAPTNPSR1ERN1ALDH1A1RAB9A | |
| SCHEMBL7115708 | 0.82 | FBP1 (0.42) | MAPTNPSR1ERN1ALDH1A1RAB9A | |
| SCHEMBL1070703 | 0.81 | FBP1 (0.62) | MAPTNPSR1ERN1MAOBALDH1A1 | |
| SCHEMBL1070702 | 0.81 | FBP1 (0.62) | MAPTNPSR1ERN1MAOBALDH1A1 | |
| SCHEMBL11797374 | 0.81 | MAOB (0.56) | MAPTNPSR1ERN1MAOBALDH1A1 | |
| SCHEMBL11797376 | 0.81 | MAOB (0.56) | MAPTNPSR1ERN1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248873-A | Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-03 | — | — | US | disclosed |