SCHEMBL11367809

SCHEMBL11367809

O=c1n(-c2ccc(F)cc2)c(=S)n2n1CCCC2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
RAB9A P51151 3/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 2/20 0.39
NPC1 O15118 2/20 0.39
KDM4E B2RXH2 2/20 0.39
GSK3A P49840 1/20 0.39
GSK3B P49841 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 1/20 0.38
GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11370412 0.88 ALDH1A1 (0.44) ALDH1A1RAB9AMAPTHPGDNPC1
SCHEMBL11362160 0.88 ALDH1A1 (0.49) ALDH1A1RAB9AMAPTHPGDNPC1
SCHEMBL11368074 0.85 ALDH1A1 (0.47) ALDH1A1RAB9AMAPTHPGDNPC1
SCHEMBL11363281 0.83 ALDH1A1 (0.39) ALDH1A1
SCHEMBL11361458 0.83 POLB (0.40) ALDH1A1MAPTHPGDKDM4EGSK3A
SCHEMBL11377938 0.83 ALDH1A1 (0.46) ALDH1A1RAB9AMAPTHPGDNPC1
SCHEMBL11358886 0.83 ALDH1A1 (0.46) ALDH1A1RAB9AMAPTHPGDNPC1
SCHEMBL11366836 0.83 ALDH1A1 (0.41) ALDH1A1RAB9AMAPTHPGDNPC1
SCHEMBL11361649 0.82 ALDH1A1 (0.43) ALDH1A1RAB9AMAPTHPGDNPC1
SCHEMBL11369619 0.82 POLB (0.42) ALDH1A1RAB9AHPGDNPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4249934-A 1,2-Alkylene-4-substituted urazole herbicides MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1981-02-10 US claimed
US-4249934-A 1,2-Alkylene-4-substituted urazole herbicides MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1981-02-10 US disclosed