Benzyl Benzylcarbamate

Benzyl Benzylcarbamate

SCHEMBL1136818

O=C(NCc1ccccc1)OCc1ccccc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.70
LMNA P02545 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
HTT P42858 1/20 0.63
HDAC3 O15379 1/20 0.62
HDAC1 Q13547 1/20 0.62
HDAC2 Q92769 1/20 0.62
NAMPT P43490 1/20 0.58
TNKS O95271 1/20 0.58
TNKS2 Q9H2K2 1/20 0.58
KEAP1 Q14145 2/20 0.57
NFE2L2 Q16236 2/20 0.57
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA9 Q16790 1/20 0.56
PRSS1 P07477 1/20 0.55
TPSAB1 Q15661 1/20 0.55
TPSD1 Q9BZJ3 1/20 0.55
TPSG1 Q9NRR2 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzyl Benzylcarbamate SCHEMBL9998166 0.98 PLAU (0.68) PLAULMNASMN1; SMN2HTTHDAC3
Benzyl Benzylcarbamate SCHEMBL19810513 0.98 PLAU (0.68) PLAULMNASMN1; SMN2HTTHDAC3
Benzyl Benzylcarbamate SCHEMBL28413454 0.98 PLAU (0.68) PLAULMNASMN1; SMN2HTTHDAC3
Benzyl Benzylcarbamate SCHEMBL29011837 0.95 PLAU (0.65) PLAULMNASMN1; SMN2HTTHDAC3
SCHEMBL191161 0.93 PLAU (0.68) PLAULMNASMN1; SMN2HTTHDAC3
SCHEMBL20047179 0.92 PLAU (0.66) PLAULMNASMN1; SMN2HTTHDAC3
SCHEMBL17864888 0.91 LMNA (0.61) PLAULMNASMN1; SMN2HTTHDAC3
SCHEMBL3418885 0.90 PLAU (0.64) PLAULMNASMN1; SMN2HTTHDAC3
SCHEMBL192484 0.90 PLAU (0.64) PLAULMNASMN1; SMN2HTTHDAC3
SCHEMBL3183198 0.90 PLAU (0.68) PLAULMNASMN1; SMN2HTTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2834313-A1 CROSSLINKABLE COMPOSITION COMPRISING PHOTOBASE GENERATORS 3M Innovative Properties Company (US) 2015-02-11 EP claimed
WO-2013151739-A1 CROSSLINKABLE COMPOSITION COMPRISING PHOTOBASE GENERATORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-10-10 WO claimed
CN-101421268-A Pyrazoloquinolones as potent PARP inhibitors ABBOTT LAB (US) 2009-04-29 CN claimed
EP-1060178-B1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES PFIZER (US) 2003-09-03 EP claimed
US-6610707-B1 Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. PFIZER INC. 2003-08-26 US claimed
EP-1021424-A1 THIADIAZOLE AMIDE MMP INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 2000-07-26 EP claimed
US-6043254-A ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR BOEHRINGER INGELHEIM PHARMA KG (DE) 2000-03-28 US claimed
WO-1997048688-A1 THIADIAZOLE AMIDE MMP INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 1997-12-24 WO claimed
EP-4426299-A1 DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME Adcentrx Therapeutics Inc. (US) 2024-09-11 EP disclosed
CN-112654630-B Tetradentate diaminodiphosphine ligands, transition metal complexes, methods for their production and use thereof 高砂香料工业株式会社 2024-05-24 CN disclosed
EP-4210883-B1 INVESTMENT CASTING COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-02-14 EP disclosed
US-20230348667-A1 Investment Casting Compositions and Methods 3M INNOVATIVE PROPERTIES COMPANY 2023-11-02 US disclosed
WO-2023081232-A1 DRUG CONJUGATES AND METHODS OF PREPARING AND USING THE SAME ADCENTRX THERAPEUTICS INC. (US) 2023-05-11 WO disclosed
CN-114945572-A HBF pharmacological inducing compounds for the treatment of sickle cell anemia and beta-thalassemia 刘扶东 2022-08-26 CN disclosed
EP-0678514-A1 3,5-Disubstituted tetrahydrofuran-2-ones CIBA-GEIGY AG (CH) 1995-10-25 EP disclosed
WO-1994008953-A1 PROCESS FOR PREPARING ISOCYANATE AND CARBAMATE ESTER PRODUCTS MONSANTO COMPANY (US) 1994-04-28 WO disclosed
US-5233010-A Reacting carbon dioxide and an aromatic diamine in an aprotic solvent and a base to produce a carbamate salt; dehydration; reacting an amide with nitrobenzene and reducing to obtain the amine MONSANTO COMPANY (US) 1993-08-03 US disclosed
CN-1039028-A The preparation method of novel cpd HAESSLE AB (SE) 1990-01-24 CN disclosed
US-3936452-A Process of producing pyrimidyl thiocarbonates NITTO BOSEKI CO., LTD. (JA) 1976-02-03 US disclosed
US-3932375-A PROTECTING GROUPS NITTO BOSEKI CO. LTD. (JA) 1976-01-13 US disclosed