Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369154 | 0.97 | GPR119 (0.60) | GPR119HRH3KCNH2ADRA2CSLC6A3 | |
| SCHEMBL11368300 | 0.84 | GPR119 (0.55) | GPR119HRH3KCNH2 | |
| SCHEMBL11366599 | 0.83 | GPR119 (0.63) | GPR119HRH3KCNH2ADRA2CSLC6A3 | |
| SCHEMBL11374409 | 0.83 | GPR119 (0.63) | GPR119HRH3KCNH2ADRA2CSLC6A3 | |
| SCHEMBL11365384 | 0.83 | HRH3 (0.51) | GPR119HRH3KCNH2ADRA2CSLC6A3 | |
| SCHEMBL10995561 | 0.83 | HRH3 (0.53) | GPR119HRH3KCNH2ADRA2CSLC6A3 | |
| SCHEMBL11369319 | 0.83 | HRH3 (0.51) | GPR119HRH3KCNH2ADRA2CSLC6A3 | |
| SCHEMBL11092220 | 0.83 | GPR119 (0.60) | GPR119HRH3 | |
| Hydrochloric Acid SCHEMBL11367458 | 0.82 | HRH3 (0.52) | GPR119HRH3KCNH2ADRA2CSLC6A3 | |
| SCHEMBL11362311 | 0.80 | HRH3 (0.49) | GPR119HRH3KCNH2ADRA2CSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4271163-A | HYPOTENSIVE AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |