Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380677 | 0.87 | ABL1 (0.44) | ABL1ALOX5PTGS1PTGS2ROCK1 | |
| SCHEMBL11384175 | 0.81 | ABL1 (0.44) | ABL1ALOX5PTGS1PTGS2 | |
| SCHEMBL7714570 | 0.79 | ABL1 (0.42) | ABL1ALOX5PTGS1PTGS2ROCK1 | |
| SCHEMBL7719900 | 0.75 | ABL1 (0.57) | ABL1ALOX5PTGS1PTGS2ALOX15 | |
| SCHEMBL7721910 | 0.73 | ALOX5 (0.61) | ABL1ALOX5PTGS1PTGS2 | |
| SCHEMBL11371045 | 0.73 | ALOX5 (0.43) | ABL1ALOX5PTGS1PTGS2 | |
| SCHEMBL11376464 | 0.72 | ABL1 (0.53) | ABL1ALOX5PTGS1PTGS2 | |
| SCHEMBL11378762 | 0.71 | ABL1 (0.61) | ABL1ALOX5PTGS1PTGS2 | |
| SCHEMBL11380671 | 0.70 | ABL1 (0.51) | ABL1ALOX5PTGS1PTGS2 | |
| SCHEMBL11376579 | 0.70 | ALOX5 (0.46) | ABL1ALOX5PTGS1PTGS2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268436-A | OXIDATIVE DIAZOTIZATION WITH NITROSYLSULFURIC ACID, ALKALINE METAL NITRITES, OR ALKYL NITRITES | AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) | 1981-05-19 | — | — | US | disclosed |