Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224637 | 0.91 | HTR2A (0.35) | PIK3CDL3MBTL1HTR2AHTR2CCHRNA7 | |
| Hydrochloric Acid SCHEMBL3222393 | 0.89 | HTR2A (0.34) | PIK3CDHTR2AHTR2CCHRNA7 | |
| SCHEMBL736492 | 0.84 | CHRNA7 (0.42) | OPRM1PIK3CDCHRNA7 | |
| SCHEMBL30623589 | 0.81 | GRM2 (0.30) | KMT2A | |
| SCHEMBL30623558 | 0.81 | GRM2 (0.31) | PIK3CD | |
| SCHEMBL4457098 | 0.78 | CHRNA7 (0.32) | PIK3CDCHRNA7 | |
| SCHEMBL4458414 | 0.75 | CHRNA7 (0.38) | OPRM1CHRNA7 | |
| SCHEMBL30623733 | 0.75 | GRIN1 (0.30) | — | |
| SCHEMBL11371915 | 0.74 | SIGMAR1 (0.52) | KMT2AOPRM1 | |
| SCHEMBL6620481 | 0.74 | AKR1B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255432-A | ANTIHYPERTENSIVE AGENTS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, ANTIVASOSPASTIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4244961-A | 1-Oxa-3,8-diazaspiro[4.5]decan-2-ones antihypertensive agents | SYNTEX (U.S.A.) INC. (US) | 1981-01-13 | — | — | US | disclosed |