Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17373573 | 0.88 | PPARA (0.53) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL17373574 | 0.88 | PPARA (0.53) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL9089268 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL9089276 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL9089274 | 0.86 | ITGB3 (0.58) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL11455855 | 0.84 | ITGB3 (0.56) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL11381983 | 0.84 | PPARA (0.44) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL11370281 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL27757439 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BPPARAPPARGPTPN1 | |
| SCHEMBL27757441 | 0.83 | ITGB3 (0.61) | ITGB3ITGA2BPPARAPPARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4288364-A | REACTING A 3-/2-HYDROXYIMINOACETYLAMINO/-2-OXOAZETIDINE WITH AN ORGANIC CARBONATE OR ACYL HALIDE | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| EP-0005507-A1 | Process for the fragmentation of 3-(2-hydroxyimino-acetylamino)-2-oxo azetidin compounds and compounds obtained thereby | CIBA-GEIGY AG (CH) | 1979-11-28 | — | — | EP | disclosed |