Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | TTR | P02766 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368076 | 0.88 | AKR1B1 (0.61) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11866266 | 0.86 | TP53 (0.60) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11375812 | 0.81 | AKR1B1 (0.64) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11866390 | 0.81 | AKR1B1 (0.62) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11767745 | 0.79 | AKR1B1 (0.52) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11371242 | 0.78 | AKR1B1 (0.70) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11863355 | 0.78 | AKR1B1 (0.59) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11371017 | 0.78 | AKR1B1 (1.00) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL68189 | 0.77 | TTR (0.83) | AKR1B1TTRTP53KMT2AKDM4E | |
| SCHEMBL11860749 | 0.77 | KDM4E (0.63) | AKR1B1TTRTP53KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250097-A | (7-METHYL(2-HYDROXYETHYL)AMINO)SULFONYLXANTHONE-2-CARBOXYLIC ACID; ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1981-02-10 | — | — | US | disclosed |
| US-4232040-A | XANTHONE CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1980-11-04 | — | — | US | disclosed |