Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.40 |
| ▸ | RHEB | Q15382 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10578214 | 0.91 | POLB (0.45) | KMT2AKDM4ERAD52POLBTDP1 | |
| SCHEMBL11372794 | 0.87 | DDAH1 (0.54) | KMT2APOLBNPC1RAB9ADDAH1 | |
| Hydrochloric Acid SCHEMBL11376325 | 0.83 | KMT2A (0.48) | KMT2AKDM4ERAD52UBE2NPOLB | |
| SCHEMBL4241945 | 0.80 | MAPT (0.51) | KMT2AKDM4EDDAH1RHEBHSD17B10 | |
| SCHEMBL10955417 | 0.80 | TDP1 (0.41) | POLBNPC1RAB9ADDAH1RHEB | |
| SCHEMBL10578208 | 0.79 | KMT2A (0.55) | KMT2AKDM4ERAD52UBE2NPOLB | |
| SCHEMBL6757230 | 0.79 | KMT2A (0.60) | KMT2AKDM4EPOLBNPC1RAB9A | |
| SCHEMBL12348255 | 0.78 | S1PR4 (0.49) | KMT2APOLBNPC1RAB9A | |
| SCHEMBL10030890 | 0.78 | TDP1 (0.49) | KMT2AKDM4EPOLBDDAH1TDP1 | |
| SCHEMBL8807127 | 0.78 | MAPT (0.55) | KMT2AKDM4ERAD52NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243806-A | ANTIALLERGENS; ANTIHISTAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-01-06 | — | — | US | disclosed |
| US-4179505-A | ANTIALLERGENS; ANTIHISTAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |