DDAH1

N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 · O94760 · DDAH1 on Sugi Atlas →

15,473 patent compounds predicted against DDAH1, 9,761 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL156221	0.64	7/20
SCHEMBL43288	0.69	6/20
Arginine (SCHEMBL43261)	0.68	6/20
Arginine (SCHEMBL288835)	0.68	6/20
Arginine (SCHEMBL288993)	0.68	6/20
SCHEMBL196828	0.63	6/20
Tilarginine (SCHEMBL349879)	0.58	6/20
SCHEMBL232480	0.64	5/20
SCHEMBL80890	0.51	5/20
L-Citrulline (SCHEMBL20587)	0.54	4/20
L-Citrulline (SCHEMBL20588)	0.54	4/20
L-Citrulline (SCHEMBL215403)	0.54	4/20
L-Citrulline (SCHEMBL288641)	0.54	4/20
L-Citrulline (SCHEMBL437142)	0.54	4/20
L-Citrulline (SCHEMBL366090)	0.53	4/20
L-Citrulline (SCHEMBL366091)	0.53	4/20
Arginine (SCHEMBL1790)	0.51	4/20
Arginine (SCHEMBL1791)	0.51	4/20
Arginine (SCHEMBL29456)	0.51	4/20
SCHEMBL156220	0.51	4/20

Clinical trials — most relevant to DDAH1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
L-arginine Treatment in Mild Hypertension	PHASE4	UNKNOWN
Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitors on Sarcopenia in Hemodialysis Patients	PHASE4	NOT_YET_RECRUITING
Obeticholic Acid Among Chronic HBV Patients with Hepatic Steatosis : Clinical and Portal Doppler Outcomes	PHASE3	NOT_YET_RECRUITING
L-Arginine in Pre-Eclampsia	PHASE3	COMPLETED
Pharmacogenetics of Disulfiram for Cocaine	PHASE2	COMPLETED
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Safety and Impact of Dasatinib on Viral Persistence and Inflammation in People With HIV Under Antiretroviral Treatment	PHASE2	COMPLETED
Desferal Administration to Improve the Impaired Reaction to Hypoxia in Diabetes	PHASE2	UNKNOWN
STRETCH Study: Effect of Distensibility on Endothelial-Dependent Vasoreactivity in Patients With ISH	PHASE2	COMPLETED
Sodium-Endothelial Function-CKD Study	nan	COMPLETED
The Clinical Value of the Nitric Oxide System Components in Asthma and COPD	nan	UNKNOWN
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions	nan	RECRUITING
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
Sodium Transport: Genetics and Hypertension	nan	COMPLETED
Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome	nan	UNKNOWN
Using Next-generation Sequencing in the Diagnosis of Epilepsy and/or Intellectual Disability in a Pediatric Cohorte	nan	COMPLETED
External Nitric Oxide Measurement Through SNO Degradation	nan	ENROLLING_BY_INVITATION
In Vivo Assessment of Histamine Pharmacodynamics	nan	WITHDRAWN
Association Between a Multi-Gene Panel and Renal Denervation Effectiveness in Patients With Hypertension	nan	UNKNOWN
Genetic DAO Deficiency and Lower Urinary Tract Symptoms	nan	COMPLETED
Identification of Acute Intermittent Porphyria Modifying Genes	nan	RECRUITING
Primary Hyperoxaluria Mutation Genotyping/Phenotyping	nan	COMPLETED
Human Epilepsy Genetics--Neuronal Migration Disorders Study	nan	RECRUITING
Predictors of Outcome of Pediatric Renal Transplantation	nan	NOT_YET_RECRUITING
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Thermogenic Silencer Regulatory Factors in Humans	nan	ACTIVE_NOT_RECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA	nan	RECRUITING
Genetic Studies of Lysosomal Storage Disorders	nan	ENROLLING_BY_INVITATION
DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a DDAH1 binder may also engage these)

Protein	Name	Similarity
Q9CWS0	—	1.000	Q9CWS0 →
P56965	—	1.000	P56965 →
O08557	—	1.000	O08557 →
Q5R5F8	—	0.960	Q5R5F8 →
Q4R4U1	—	0.960	Q4R4U1 →
Q9NVE7	—	0.959	Q9NVE7 →
Q8K183	—	0.955	Q8K183 →
O46560	—	0.953	O46560 →
Q923S8	—	0.951	Q923S8 →
O35331	—	0.948	O35331 →
PDXK	Pyridoxal kinase	0.947	landscape →
P82197	—	0.946	P82197 →
Q0II59	—	0.946	Q0II59 →
Q9H2P9	—	0.945	Q9H2P9 →
A2VE01	—	0.944	A2VE01 →
Q5ZJL4	—	0.943	Q5ZJL4 →
Q5PQL4	—	0.943	Q5PQL4 →
Q5U4X8	—	0.943	Q5U4X8 →
Q5E982	—	0.941	Q5E982 →
TRPM2	Transient receptor potential cation channel subfamily M member 2	0.941	landscape →
Q92989	—	0.941	Q92989 →
Q91YD4	—	0.940	Q91YD4 →
Q9D7B1	—	0.940	Q9D7B1 →
Q9CWQ0	—	0.939	Q9CWQ0 →
Q99LI9	—	0.939	Q99LI9 →
Q5ZM83	—	0.939	Q5ZM83 →
Q4R7R3	—	0.939	Q4R7R3 →
Q8R4N0	—	0.939	Q8R4N0 →
Q920M5	—	0.939	Q920M5 →
Q5I0K3	—	0.939	Q5I0K3 →