Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088915 | 0.80 | AKT1 (0.46) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL4463941 | 0.80 | LMNA (0.41) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL6802648 | 0.79 | LMNA (0.45) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL1772002 | 0.79 | LMNA (0.47) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL5757395 | 0.79 | POLB (0.47) | AKT1LMNAPOLB | |
| SCHEMBL13980666 | 0.78 | AKT1 (0.44) | AKT1LMNAPOLB | |
| SCHEMBL5857 | 0.78 | CYP17A1 (0.49) | SLC6A2MMP12MMP13 | |
| SCHEMBL5871517 | 0.77 | LMNA (0.48) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL2487493 | 0.77 | LMNA (0.46) | CA12CA1CA7CA14AKT1 | |
| SCHEMBL6502501 | 0.77 | LMNA (0.43) | CA12CA1CA7CA14AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |