Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.62 |
| ▸ | PTPN5 | P54829 | 16/20 | 0.62 |
| ▸ | PTPN2 | P17706 | 14/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427116 | 0.81 | METAP2 (0.51) | PTPN1PTPN5PTPN2MAPTKDM4E | |
| SCHEMBL26073482 | 0.79 | AGPAT2 (0.49) | MAPTKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL11231219 | 0.76 | KDM4E (0.66) | PTPN1PTPN5PTPN2KDM4EALDH1A1 | |
| SCHEMBL26050351 | 0.76 | KDM4E (0.74) | MAPTKDM4EALDH1A1MEN1HPGD | |
| SCHEMBL6085198 | 0.76 | PTPN1 (0.61) | PTPN1PTPN5PTPN2MAPTKDM4E | |
| SCHEMBL24270367 | 0.75 | MAPT (0.52) | PTPN1PTPN5PTPN2MAPTKDM4E | |
| SCHEMBL2243342 | 0.75 | PTPN1 (1.00) | PTPN1PTPN5PTPN2MAPTKDM4E | |
| SCHEMBL11006648 | 0.74 | PIK3CD (0.62) | PTPN1PTPN5PTPN2MAPTKDM4E | |
| SCHEMBL31701131 | 0.74 | PTPN1 (1.00) | PTPN1PTPN5PTPN2MAPTKDM4E | |
| SCHEMBL4494186 | 0.73 | MAPT (0.69) | MAPTKDM4EALDH1A1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021304-A1 | Coumarin compounds, their preparation and their use as dyestuffs | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |