Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11374291 | 0.83 | ATM (0.47) | ATMTDP1L3MBTL1PBRM1FFAR4 | |
| SCHEMBL4426521 | 0.78 | HDAC3 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL4426518 | 0.78 | HDAC3 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL4426516 | 0.78 | HDAC3 (0.49) | ALDH1A1MAPTSMN1; SMN2LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL9527737 | 0.77 | HDAC3 (0.48) | MAPTSMN1; SMN2CYP3A4MAPK1GAA | |
| SCHEMBL26817317 | 0.76 | EDNRB (0.43) | TDP1L3MBTL1PLA2G1BATG4BALDH1A1 | |
| SCHEMBL26816636 | 0.76 | EDNRB (0.43) | TDP1L3MBTL1PLA2G1BATG4BALDH1A1 | |
| SCHEMBL26816647 | 0.76 | EDNRB (0.43) | TDP1L3MBTL1PLA2G1BATG4BALDH1A1 | |
| SCHEMBL11359606 | 0.71 | ATM (0.50) | ATMTDP1L3MBTL1PBRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11374295 | 0.70 | ATM (0.48) | ATMTDP1L3MBTL1PBRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269848-A | ANTIINFLAMMATORY AGENTS; ANALGESICS; ANTIPYRETICS | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1981-05-26 | — | — | US | disclosed |