Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 2/20 | 0.43 |
| ▸ | EDNRA | P25101 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26816647 | 1.00 | EDNRB (0.43) | EDNRBEDNRAKDM1ACAMK2AADRA2A | |
| SCHEMBL26817317 | 1.00 | EDNRB (0.43) | EDNRBEDNRAKDM1ACAMK2AADRA2A | |
| SCHEMBL26656414 | 0.87 | OPRM1 (0.41) | EDNRBEDNRACAMK2AADRA2APNMT | |
| SCHEMBL10875369 | 0.81 | ALDH1A1 (0.42) | SRD5A1SRD5A2HTR2AHTR2CHTR2B | |
| SCHEMBL26816616 | 0.80 | TDP2 (0.43) | L3MBTL1POLBALDH1A1MEN1KMT2A | |
| SCHEMBL4426521 | 0.76 | HDAC3 (0.49) | EDNRBEDNRAOPRM1HDAC3HDAC4 | |
| SCHEMBL4426518 | 0.76 | HDAC3 (0.49) | EDNRBEDNRAOPRM1HDAC3HDAC4 | |
| SCHEMBL4426516 | 0.76 | HDAC3 (0.49) | EDNRBEDNRAOPRM1HDAC3HDAC4 | |
| SCHEMBL11370877 | 0.76 | ATM (0.47) | TDP1L3MBTL1SRD5A2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9527737 | 0.75 | HDAC3 (0.48) | KDM1AOPRM1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225162-A1 | ANTIVIRAL INDOLINYL COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2023-11-23 | — | — | WO | disclosed |