Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1370758 | 0.81 | KDM4E (0.59) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL11709052 | 0.79 | KDM4E (0.57) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL30274765 | 0.79 | KDM4E (0.57) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL18499080 | 0.79 | KDM4E (0.57) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL12998212 | 0.78 | HSD17B10 (0.54) | KDM4EHSD17B10HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL17505183 | 0.78 | KDM4E (0.50) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL3599325 | 0.77 | GRIA1 (0.47) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL4542466 | 0.73 | HCAR2 (0.39) | KDM4EHSD17B10HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL31154597 | 0.72 | CYP2A6 (0.53) | KDM4EHSD17B10HPGDALDH1A1TSHR | |
| SCHEMBL1709827 | 0.72 | BRD4 (0.59) | KDM4EHSD17B10HPGDL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284787-A | Process for the preparation of 1,2,3-triazoles substituted in the 2-position | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| EP-0004897-B1 | PROCESS FOR THE PREPARATION OF 1,2,3 TRIAZOLES SUBSTITUTED IN THE 2-POSITION | BAYER AG (DE) | 1981-03-18 | — | — | EP | disclosed |
| EP-0004897-A2 | Process for the preparation of 1,2,3 triazoles substituted in the 2-position | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |