Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709052 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL30274765 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL1370758 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL13349416 | 0.87 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL9254420 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL1263927 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL31154599 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL7646960 | 0.81 | DAO (0.53) | KDM4EALDH1A1HSD17B10HPGDCYP1A2 | |
| Bromide SCHEMBL31326904 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL24853036 | 0.80 | IL4I1 (0.55) | KDM4EALDH1A1HSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566284-B2 | Agents and methods for treating ischemic and other diseases | NONO INC. (CA) | 2017-02-14 | — | — | US | disclosed |
| US-9566284-B2 | Agents and methods for treating ischemic and other diseases | NONO INC. (CA) | 2017-02-14 | — | — | US | disclosed |