Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447050 | 1.00 | SERPINE1 (0.46) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL28446906 | 0.91 | SERPINE1 (0.44) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL5664340 | 0.91 | SERPINE1 (0.44) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL15142163 | 0.91 | SERPINE1 (0.44) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL28064168 | 0.87 | SERPINE1 (0.57) | SERPINE1L3MBTL1PTPN2PTPN1PTPN11 | |
| SCHEMBL20530411 | 0.87 | SERPINE1 (0.57) | SERPINE1L3MBTL1PTPN2PTPN1PTPN11 | |
| SCHEMBL4163000 | 0.86 | SERPINE1 (0.46) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL28444407 | 0.86 | SERPINE1 (0.46) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL31485713 | 0.85 | SERPINE1 (0.47) | SERPINE1POLBKDM4ELMNAGAA | |
| SCHEMBL20578325 | 0.85 | SERPINE1 (0.47) | SERPINE1POLBKDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375803-B | Screening method of anti-inflammatory active component ethyl gallate in gallnut and application thereof | 石河子大学 | 2024-05-07 | — | — | CN | claimed |
| CN-111198240-B | Method for extracting 1, 2, 6 tri-galloyl glucose from tea | 中国农业科学院茶叶研究所 | 2022-09-09 | — | — | CN | claimed |
| CN-110652505-B | Application of Trapa acornis nakai shell polyphenol extract in preparation of medicine for resisting HER-2 over-expression type breast cancer | 嘉兴学院 | 2022-05-31 | — | — | CN | claimed |
| CN-109453212-B | A fructus Terminaliae Billericae extract with anticancer effect and its effective components preparation method | 北京中医药大学 | 2021-12-14 | — | — | CN | claimed |
| CN-113195245-A | Rubber composition based on at least one functionalized elastomer comprising polar functional groups and specific polyphenolic compounds | 米其林集团总公司 | 2021-07-30 | — | — | CN | claimed |
| CN-110652529-B | Application of Trapa acornis nakai shell polyphenol extract in preparation of drug for resisting triple negative breast cancer | 嘉兴学院 | 2021-06-08 | — | — | CN | claimed |
| US-20210146003-A1 | A NOVEL METHOD TO IMPROVE ADHESIVE STRENGTH OF REVERSIBLE POLYMERS AND HYDROGELS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2021-05-20 | — | — | US | claimed |
| CN-111624269-A | Method for screening drug effect substances for treating adenomyosis in cassia twig and poria cocos pills | 山东中医药大学附属医院 | 2020-09-04 | — | — | CN | claimed |
| WO-2020127888-A2 | URBAN DARKENING SKIN COMPOSITION AND FORMULATION | ORIFLAME COSMETICS AG (CH) | 2020-06-25 | — | — | WO | claimed |
| CN-110652505-A | Application of Trapa acornis nakai shell polyphenol extract in preparation of medicine for resisting HER-2 over-expression type breast cancer | 嘉兴学院 | 2020-01-07 | — | — | CN | claimed |
| CN-104535677-B | A kind of moutan bark medicinal material based on screening active ingredients and preparation detection method | Jiangsu Provincial Insititute of Traditional Chinese Medicine (CN) | 2016-03-23 | — | — | CN | claimed |
| CN-104535677-A | Tree peony bark medicinal material based on activity screening and preparation detecting method | JIANGSU PROVINCIAL ACADEMY TRADITIONAL CHINESE MED | 2015-04-22 | — | — | CN | claimed |
| CN-102805767-B | Heat stranguria removal granule raw material polygonum capitatum extract with anti-gonococcus effect | GUIZHOU WARMEN PHARMACEUTICAL CO LTD | 2014-04-16 | — | — | CN | claimed |
| CN-102772499-B | Effective parts obtained by alcohol extraction of raw materials of Relingqing granules as well as preparation method and applications thereof | GUIZHOU WARMEN PHARMACEUTICAL CO LTD | 2014-01-08 | — | — | CN | claimed |
| CN-102805767-A | Heat stranguria removal granule raw material polygonum capitatum extract with anti-gonococcus effect | GUIZHOU WARMEN PHARMACEUTICAL CO LTD | 2012-12-05 | — | — | CN | claimed |
| CN-102772499-A | Effective parts obtained by alcohol extraction of raw materials of Relingqing granules as well as preparation method and applications thereof | GUIZHOU WARMEN PHARMACEUTICAL CO LTD | 2012-11-14 | — | — | CN | claimed |
| EP-1545554-A4 | METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS | UNIV OHIO (US) | 2006-06-14 | — | — | EP | claimed |
| US-20060058243-A1 | Methods and compositions for treating diabetes mellitis | OHIO UNIVERSITY | 2006-03-16 | — | — | US | claimed |
| EP-1545554-A1 | METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS | Ohio University (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004009094-A1 | METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS | OHIO UNIVERSITY (US) | 2004-01-29 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058243-A1 | Methods and compositions for treating diabetes mellitis | IAPP, GCG, MTPN | SERPINE1 196/4885POLB 4432/4885KDM4E 2698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.