SCHEMBL5664340

SCHEMBL5664340

O=C[C@H](OC(=O)c1cc(O)c(O)c(O)c1)[C@@H](OC(=O)c1cc(O)c(O)c(O)c1)[C@H](O)[C@H](O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 8/20 0.44
PTPN2 P17706 1/20 0.37
PTPN1 P18031 1/20 0.37
PTPN11 Q06124 1/20 0.37
POLB P06746 2/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
NFKB1 P19838 1/20 0.37
XDH P47989 1/20 0.37
GFER P55789 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
FUT7 Q11130 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ESR1 P03372 2/20 0.35
AKR1C4 P17516 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15142163 1.00 SERPINE1 (0.44) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL28446906 1.00 SERPINE1 (0.44) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL28447050 0.91 SERPINE1 (0.46) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL1137255 0.91 SERPINE1 (0.46) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL20578325 0.89 SERPINE1 (0.47) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL31485713 0.89 SERPINE1 (0.47) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL1159921 0.89 SERPINE1 (0.47) SERPINE1PTPN2PTPN1PTPN11POLB
Gallic Acid SCHEMBL10712693 0.88 POLB (0.36) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL17156389 0.88 SERPINE1 (0.46) SERPINE1PTPN2PTPN1PTPN11POLB
SCHEMBL28178896 0.88 SERPINE1 (0.46) SERPINE1PTPN2PTPN1PTPN11POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111624269-A Method for screening drug effect substances for treating adenomyosis in cassia twig and poria cocos pills 山东中医药大学附属医院 2020-09-04 CN claimed
US-20190390090-A1 ADHESIVE FOR PELLICLE, PELLICLE FOR PHOTO MASK AND METHOD FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-12-26 US claimed
CN-102772499-B Effective parts obtained by alcohol extraction of raw materials of Relingqing granules as well as preparation method and applications thereof GUIZHOU WARMEN PHARMACEUTICAL CO LTD 2014-01-08 CN claimed
CN-102772499-A Effective parts obtained by alcohol extraction of raw materials of Relingqing granules as well as preparation method and applications thereof GUIZHOU WARMEN PHARMACEUTICAL CO LTD 2012-11-14 CN claimed
EP-1545554-A4 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS UNIV OHIO (US) 2006-06-14 EP claimed
US-20060058243-A1 Methods and compositions for treating diabetes mellitis OHIO UNIVERSITY 2006-03-16 US claimed
EP-1545554-A1 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS Ohio University (US) 2005-06-29 EP claimed
WO-2004009094-A1 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS OHIO UNIVERSITY (US) 2004-01-29 WO claimed
US-12258494-B2 Adhesive for pellicle, pellicle for photo mask and method for manufacturing the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-03-25 US disclosed
CN-118203695-A Sprayable hydrogel and preparation method and application thereof 石河子大学 2024-06-18 CN disclosed
CN-112375803-B Screening method of anti-inflammatory active component ethyl gallate in gallnut and application thereof 石河子大学 2024-05-07 CN disclosed
US-20240091170-A1 Catechol Nanoparticle, Catechol Protein Nanoparticle, and Preparation Method and Use Thereof SHIHEZI UNIVERSITY (CN) 2024-03-21 US disclosed
US-20230399552-A1 ADHESIVE FOR PELLICLE, PELLICLE FOR PHOTO MASK AND METHOD FOR MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2023-12-14 US disclosed
CN-115300496-B Catechol nanoparticle, catechol protein nanoparticle, and preparation methods and applications thereof 石河子大学 2023-09-26 CN disclosed
US-20130004936-A1 SUPERCOOLING PROMOTING AGENT NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSIT (JP) 2013-01-03 US disclosed
CN-102772499-A Effective parts obtained by alcohol extraction of raw materials of Relingqing granules as well as preparation method and applications thereof GUIZHOU WARMEN PHARMACEUTICAL CO LTD 2012-11-14 CN disclosed
EP-1545554-A4 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS UNIV OHIO (US) 2006-06-14 EP disclosed
US-20060058243-A1 Methods and compositions for treating diabetes mellitis OHIO UNIVERSITY 2006-03-16 US disclosed
EP-1545554-A1 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS Ohio University (US) 2005-06-29 EP disclosed
WO-2004009094-A1 METHODS AND COMPOSITIONS FOR TREATING DIABETES MELLITIS OHIO UNIVERSITY (US) 2004-01-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060058243-A1 Methods and compositions for treating diabetes mellitis IAPP, GCG, MTPN SERPINE1 196/4885PTPN2 2187/4885PTPN1 1169/4885
US-20130004936-A1 SUPERCOOLING PROMOTING AGENT TREH, HYOU1, UGGT1 SERPINE1 734/4885PTPN2 4029/4885PTPN1 3578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.