Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375195 | 0.92 | ADRB2 (0.45) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11368382 | 0.89 | ADRB3 (0.52) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11573918 | 0.83 | ADRB2 (0.46) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11373396 | 0.82 | ADRB3 (0.42) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11560551 | 0.77 | ADRB2 (0.48) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11572481 | 0.77 | ADRB3 (0.43) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11571155 | 0.76 | ADRB2 (0.47) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11563952 | 0.75 | ADRB2 (0.46) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11365572 | 0.75 | ADRB3 (0.53) | ADRB2ADRB3ADRB1 | |
| SCHEMBL11570713 | 0.74 | ADRB2 (0.46) | ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304790-A | 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof | SCHERING CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |