Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371450 | 0.88 | SMN1; SMN2 (0.50) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL4368062 | 0.83 | ALPL (0.49) | ALDH1A1ALPLRXFP1KDM4EMAPT | |
| SCHEMBL5773257 | 0.80 | MAPT (0.51) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5775506 | 0.74 | AHR (0.36) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5774926 | 0.73 | TP53 (0.44) | TP53SMN1; SMN2TSHRALPL | |
| SCHEMBL11517887 | 0.71 | POLB (0.47) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5773924 | 0.70 | MAPT (0.44) | TSHRALPLKDM4EMAPT | |
| SCHEMBL5776428 | 0.70 | SIRT2 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2ALPL | |
| SCHEMBL3054751 | 0.69 | HCRTR1 (0.43) | MEN1KMT2AALDH1A1TP53KDM4E | |
| SCHEMBL5770512 | 0.69 | MAPT (0.45) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4243406-A | REDUCING INJURIES TO CROP PLANTS WHEN USING AN ALPHA-HALOACETANILIDE AS A HERBICIDE | MONSANTO COMPANY (US) | 1981-01-06 | — | — | US | disclosed |