Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375172 | 1.00 | POLB (0.40) | POLBNOS1EPHX2AVPR1AGPBAR1 | |
| SCHEMBL10831824 | 0.93 | GPR6 (0.43) | POLBAVPR1AALDH1A1LMNAGPR6 | |
| SCHEMBL11371833 | 0.92 | KCNN4 (0.42) | ALDH1A1LMNAACHE | |
| SCHEMBL11371555 | 0.88 | GPR183 (0.39) | POLBALDH1A1LMNAGPR6CRHBP | |
| SCHEMBL11363360 | 0.87 | HPGD (0.43) | GPBAR1GPR6CRHBPCRHR2 | |
| SCHEMBL11371257 | 0.87 | RXFP1 (0.44) | AVPR1AGPBAR1ALDH1A1LMNACRHBP | |
| SCHEMBL11363350 | 0.87 | HPGD (0.43) | GPBAR1GPR6CRHBPCRHR2 | |
| SCHEMBL10832211 | 0.86 | SCN5A (0.39) | EPHX2ALDH1A1LMNAGPR6CRHBP | |
| SCHEMBL10831627 | 0.85 | MAPT (0.44) | POLBLMNAGPR6ACHE | |
| SCHEMBL10832649 | 0.85 | MGLL (0.43) | POLBALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262005-A | CONTROLLING ECTOPARASITES WHICH ATTACK CATTLE AND PIGS | THE BOOTS COMPANY LIMITED (GB) | 1981-04-14 | — | — | US | disclosed |