Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11384130 | 0.81 | KMT2A (0.56) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17290521 | 0.76 | ALDH1A1 (0.67) | KDM4EALDH1A1CDK8SMN1; SMN2MEN1 | |
| SCHEMBL11519413 | 0.75 | ALDH1A1 (0.57) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23403346 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1CDK8SMN1; SMN2MEN1 | |
| SCHEMBL23403609 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1CDK8SMN1; SMN2MEN1 | |
| SCHEMBL10961526 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11775287 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1CSF1RFGFR1FLT1 | |
| SCHEMBL17792533 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23399055 | 0.71 | ALDH1A1 (0.53) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23399304 | 0.71 | ALDH1A1 (0.53) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260776-A | PYRAZOLONE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |