Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603605 | 0.83 | PPARG (0.45) | PPARGAGTR1AGTR2CA12CA9 | |
| SCHEMBL11504340 | 0.82 | HTT (0.42) | PPARGCA12CA9HTTCYP1A2 | |
| SCHEMBL7243797 | 0.80 | PPARG (0.39) | PPARGAGTR1AGTR2CA12CA9 | |
| SCHEMBL28206798 | 0.79 | CA12 (0.40) | PPARGCA12CA9HTTCYP1A2 | |
| SCHEMBL11389628 | 0.79 | HTT (0.43) | CA12CA9HTTCYP1A2CYP2D6 | |
| SCHEMBL11396410 | 0.79 | CA12 (0.40) | PPARGAGTR1AGTR2CA12CA9 | |
| SCHEMBL11390081 | 0.79 | CA12 (0.43) | PPARGAGTR1AGTR2CA12CA9 | |
| SCHEMBL24405198 | 0.76 | CYP1A2 (0.42) | CA12CA9HTTCYP1A2CYP2D6 | |
| SCHEMBL2276554 | 0.76 | KMT2A (0.42) | PPARGCA12CA9HTTCYP1A2 | |
| SCHEMBL22368580 | 0.74 | HTR2A (0.42) | CA12CA9HTTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255432-A | ANTIHYPERTENSIVE AGENTS, ANTIHISTAMINES, BRONCHODILATOR AGENTS, ANTIVASOSPASTIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1981-03-10 | — | — | US | disclosed |