Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375390 | 0.82 | KCNH2 (0.49) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL11389394 | 0.77 | OPRM1 (0.51) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL2456174 | 0.75 | CA12 (0.50) | SMN1; SMN2LMNAMEN1ALDH1A1MAPT | |
| Fedotozine SCHEMBL1649900 | 0.74 | OPRM1 (0.63) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Fedotozine SCHEMBL154629 | 0.74 | OPRM1 (0.63) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Fedotozine SCHEMBL6418832 | 0.74 | OPRM1 (0.63) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL11372319 | 0.72 | OPRM1 (0.45) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Trimebutine SCHEMBL25705 | 0.72 | OPRM1 (1.00) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| Trimebutine SCHEMBL14273976 | 0.72 | OPRM1 (1.00) | OPRM1OPRD1NR1I2CHRM2ADORA3 | |
| SCHEMBL30139610 | 0.71 | TAAR1 (0.48) | OPRM1OPRD1NR1I2CHRM2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4301163-A | ANTISPASMODIC AGENTS, ANESTHETIC, ANALGESICS | SOCIETE INDUSTRIELLE DE PRODUITS DE SYNTHESE (FR) | 1981-11-17 | — | — | US | disclosed |