Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31345747 | 0.85 | SLC1A3 (0.49) | ANPEPERAP2ERAP1TSHRSLC1A3 | |
| SCHEMBL20496943 | 0.85 | SLC1A3 (0.49) | ANPEPERAP2ERAP1TSHRSLC1A3 | |
| SCHEMBL27725657 | 0.85 | TSHR (0.53) | ANPEPERAP2ERAP1TSHRGRM8 | |
| SCHEMBL29254196 | 0.84 | TSHR (0.56) | ANPEPERAP2ERAP1TSHRLOXL2 | |
| SCHEMBL29254199 | 0.84 | TSHR (0.56) | ANPEPERAP2ERAP1TSHRLOXL2 | |
| SCHEMBL7358695 | 0.83 | GRM8 (0.56) | ANPEPERAP2ERAP1TSHRGRM8 | |
| SCHEMBL8092467 | 0.83 | GRM8 (0.56) | ANPEPERAP2ERAP1TSHRGRM8 | |
| SCHEMBL3097653 | 0.82 | TSHR (0.61) | ANPEPERAP2ERAP1TSHRLOXL2 | |
| SCHEMBL2561037 | 0.81 | TSHR (0.56) | ANPEPERAP2ERAP1TSHRGRM8 | |
| SCHEMBL4754818 | 0.81 | TSHR (0.59) | ANPEPERAP2ERAP1TSHRLOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4260743-A | Preparation of β-lactams and intermediates therefor | GIST-BROCADES N.V. (NL) | 1981-04-07 | — | — | US | disclosed |